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Clinical Implications of Basic Research
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Volume 359:1842-1844 October 23, 2008 Number 17
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The Exercise Pill — Too Good to Be True?
Laurie J. Goodyear, Ph.D.

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Regular physical exercise has undisputed health benefits in the prevention — and in some cases, the treatment — of many diseases. The problem is that for the great majority of Americans, probably as much as 70% of the population, there is an inability or unwillingness to meet the minimum physical activity guidelines established by the American College of Sports Medicine. The idea of taking a pill to gain the benefits of exercise is extremely attractive for the millions of "couch potatoes." A recent study by Narkar et al.1 suggests that a couple of molecules could mimic some effects of exercise . . . [Full Text of this Article]


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From the Joslin Diabetes Center and Harvard Medical School, Boston.


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