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Previous Volume 361:1701-1703 October 22, 2009 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Many children with chronic kidney disease, even those in whom the disease is discovered very early, ultimately lose renal function; some ultimately progress to stage 5 chronic kidney disease (end-stage renal disease). Causes of chronic kidney disease in children differ substantially from those in adults; the largest diagnostic categories in children are congenital renal and genitourinary abnormalities; obstructive uropathy or renal hypoplasia–dysplasia are most common, followed by reflux nephropathy and focal segmental glomerulosclerosis.^1,2

Despite much evidence that blocking the renin–angiotensin system is helpful in treating adults with various nephropathies,³ comparable data from randomized, controlled trials involving children are lacking. Although . . . [Full Text of this Article]

This article has been cited by other articles:

• (2009). Intensive Blood Pressure Control Slows Progression of Chronic Kidney Disease in Children. JWatch Pediatrics 2009: 1-1 [Full Text]