Case 26-2009 -- A 34-Year-Old Man with Cystic Fibrosis with Abdominal Pain and Distention

doi:10.1056/NEJMcpc0902225

Volume 361:807-816		August 20, 2009		Number 8

Case 26-2009 — A 34-Year-Old Man with Cystic Fibrosis with Abdominal Pain and Distention

Steven D. Freedman, M.D., Ph.D., Raul N. Uppot, M.D., and Mari Mino-Kenudson, M.D.

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Presentation of Case

Dr. David M. Dudzinski (Medicine): Fever and abdominal painand distention developed in a 34-year-old man with cystic fibrosisduring an admission to this hospital for pulmonary care.

The patient was awaiting lung transplantation for end-stagelung disease due to cystic fibrosis. Cystic fibrosis had beendiagnosed at birth, and he was homozygous for the F508 mutationin the cystic fibrosis transmembrane conductance regulator gene(CFTR). He had been hospitalized at least annually for complicationsof the disease, most recently 1 year earlier because of pneumoniacaused by Pseudomonas aeruginosa and methicillin-resistant Staphylococcusaureus. His daily pulmonary . . . [Full Text of this Article]

Differential Diagnosis

Vascular Events

Obstruction

Inflammation

Infection

Management of C. difficile Colitis

Summary

Clinical Diagnosis

Dr. Steven D. Freedman's Diagnosis

Pathological Discussion

Anatomical Diagnoses

Source Information

From the Department of Medicine, Beth Israel Deaconess Medical Center (S.D.F.); the Departments of Radiology (R.N.U.) and Pathology (M.M.-K.), Massachusetts General Hospital; and the Departments of Medicine (S.D.F.), Radiology (R.N.U.), and Pathology (M.M.-K.), Harvard Medical School — all in Boston.