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Volume 361:97-98 July 2, 2009 Number 1
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Moyamoya Disease and Moyamoya Syndrome

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by Scott, R. M.
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To the Editor: As the principal investigator of a National Institutes of Health (NIH)–funded natural-history study involving North American adults with moyamoya disease,1 I read with interest the review article on this disease and moyamoya syndrome by Scott and Smith (March 19 issue).2 There is one implicit, and, I believe, invalid, assumption in this otherwise thoughtful review: that the findings of the natural-history studies involving pediatric Asian populations are applicable to North American adults. I am writing to emphasize that the natural history of North American adults with this angiographic disorder is unknown. In addition, many adult patients in North . . . [Full Text of this Article]



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